Digital bioanalysis.

Multiplexed extraction and quantitative analysis of pharmaceuticals from DBS samples using digital microfluidics.

BACKGROUND Dried blood spot (DBS) sampling is emerging as a valuable technique in a variety of fields, including clinical and preclinical testing of pharmaceuticals. Despite this popularity, current DBS sampling and analysis processes remain laborious and time consuming. Digital microfluidics, a microscale liquid-handling technique, characterized by the manipulation of discrete droplets on open...

The broadening scope of validation: towards best practices in the world of bioanalysis.

Feedback from the EBF - Focus Workshop: bringing assay validation and analysis of biomarkers into practice.

European Bioanalysis Forum Focus Workshop, Lisbon, Portugal, 9-10 June 2016 At the recent European Bioanalysis Forum's Focus Workshop 'Bringing Assay Validation and Analysis of Biomarkers into Practice', the discussion on best practice for biomarker assay validation continued. Both the presentations and the adjacent panel discussions yielded valuable food for thought for the broader bioanalytic...

32nd International Symposium on Microscale Separations and Bioanalysis (MSB 2016).

32nd International Symposium on Microscale Separations and Bioanalysis, Niagara-on-the-Lake, Canada, 3-7 April 2016 The 32nd edition of the International Symposium on Microscale Separations and Bioanalysis (MSB) was held in Niagara-on-the-Lake, Canada, from 3 to 7 April 2016. This article outlines the aim and the main distinctive features of the MSB symposium. A selection of the scientific rese...

Meeting the demands of regulatory requirements: the significance of ADME.